Link to myNCBI
Refereed Papers
Waring, A.L., J. Hill, B.M. Allen, N.M. Bretz, N. Le, P. Kr, D. Fuss, N.T. Mortimer. 2022. Meta-analysis of immune induced gene expression changes in diverse Drosophila melanogaster innate immune responses. Special Issue: Insect Bioinformatics. Insects, 13(5): 490. DOI: 10.3390/insects13050490.
Sultana, S., M.E. Crompton, K. Meurer, O. Jankiewicz, G.H. Morales, C. Johnson, E. Horbach, K.P. Hoffmann, P. Kr, R. Shah, G.M. Anderson, N.T. Mortimer, J.E. Schmitz, M. Hadjifrangiskou, A. Foti, J.U. Dahl. 2022. Redox-Mediated Inactivation of the Transcriptional Repressor RcrR is Responsible for Uropathogenic Escherichia coli's Increased Resistance to Reactive Chlorine Species. mBio, in press. DOI: 10.1128/mbio.01926-22.
Lopatto, D., et al. 2022. Student attitudes contribute to the effectiveness of a genomics CURE. J. Microbiol Biol Educ, DOI: 10.1128/jmbe.00208-21.
Thompson, C.F., K.E. Hodges, N.T. Mortimer, A.D. Vrailas-Mortimer, S.K. Sakaluk, M.E. Hauber. 2022. Avian eggshell coloration predicts shell-matrix protoporphyrin content. Canadian J of Zoology, 100: 77-81. DOI: 10.1139/cjz-2021-0134.
Mortimer, N.T., M.L. Fischer, A.L. Waring, P. Kr, B.Z. Kacsoh, S.E. Brantley, E.S. Keebaugh, J. Hill, C. Lark, J. Martin, P. Bains, J. Lee, A.D. Vrailas-Mortimer, T.A. Schlenke. 2021. Extracellular matrix protein N-glycosylation mediates immune self-tolerance in Drosophila melanogaster. PNAS, 118 (39): e2017460118. DOI: 10.1073/pnas.2017460118.
Ryan, S.M., M. Almassey, A.M. Burch, G. Ngo, J.M. Martin, D. Myers, D. Compton, S. Archie, L. Naeger, A. Salzman, A. Virola-Iarussi, M. Cross, S. Barbee, N.T. Mortimer, S. Sanyal, A.D. Vrailas-Mortimer. 2021. Drosophila p38 MAPK interacts with BAG-3/starvin to regulate age-dependent protein homeostasis. Aging Cell, 20 (11): e13481. DOI: 10.1111/acel.13481.
Calderon, S.J., S.Y. Chung, C.J. Fields, N.T. Mortimer. 2021. Children Tooth Brushing Behavior and Oral Microbiota: A Pilot Study. Oral, 1(2): 112-121. DOI: 10.3390/oral1020012.
Kr, P., J. Lee, N.T. Mortimer. 2021. The S1A protease family members CG10764 and CG4793 regulate cellular immunity in Drosophila. microPublication Biology: DOI: 10.17912/micropub.biology.000370.
Trainor, J.E., P. Kr, N.T. Mortimer. 2021. Immune Cell Production Is Targeted by Parasitoid Wasp Virulence in a Drosophila–Parasitoid Wasp Interaction. Pathogens, 10(1): 49. DOI: 10.3390/pathogens10010049.
Ryan, S.M., K. Wildman, B. Oceguera-Perez, S. Barbee, N.T. Mortimer, A. Vrailas-Mortimer. 2020. Evolutionarily Conserved Transcription Factors Drive the Oxidative Stress Response in Drosophila. J Exp Biology, 223: jeb221622. DOI: 10.1242/jeb.221622.
Sargent L., Y. Liu, W. Leung, N.T. Mortimer, D. Lopatto, J. Goecks, S.C.R. Elgin. 2020. G-OnRamp: Generating genome browsers to facilitate undergraduate-driven collaborative genome annotation. PLOS Computational Biology, 16(6): e1007863. DOI: 10.1371/journal.pcbi.1007863.
Hodges, K.E., N.T Mortimer, A.D. Vrailas-Mortimer, S.K. Sakaluk, C.F. Thompson. 2020. Connecting the dots: avian eggshell pigmentation, female condition and paternal provisioning effort. Biological Journal of the Linnean Society, 130(1): 114-127. DOI: 10.1093/biolinnean/blaa002.
Lopatto, D., et al. 2020. Facilitating Growth through Frustration: Using Genomics Research in a Course-Based Undergraduate Research Experience. J. Microbiol Biol Educ, 21(1): DOI: 10.1128/jmbe.v21i1.2005.
Alvarado, G., S.R. Holland, J. DePerez-Rasmussen, B.A. Jarvis, T. Telander, N. Wagner, A.L. Waring, A. Anast, B. Davis, A. Frank, K. Genenbacher, J. Larson, C. Mathis, A.E. Oates, N.A. Rhoades, L. Scott, J. Young, N.T. Mortimer. 2020. Bioinformatic analysis suggests potential mechanisms underlying parasitoid venom evolution and function. Genomics, 112: 1096-1104. DOI: 10.1016/j.ygeno.2019.06.022.
Leung, W., et al. 2017. Retrotransposons are the major contributors to the expansion of the Drosophila ananassae Muller F element. G3: Genes, Genomics, Genetics 7(8): 2439-2460. DOI: 10.1534/g3.117.040907.
Schachtner, L.T., I.E. Sola, D. Forand, S. Antonacci, A.J. Postovit, N.T. Mortimer, D.J. Killian, E.C. Olesnicky. 2015. Drosophila Shep and C. elegans SUP-26 are RNA-binding proteins that play diverse roles in nervous system development. Development Genes and Evolution 225(6): 319-330. DOI: 10.1007/s00427-015-0514-3.
Antonacci, S., D. Forand, M. Wolf, C. Tyus, J. Barney, L. Kellogg, M. Simon, G. Kerr, N.T. Mortimer, E.C. Olesnicky, D.J. Killian. 2015. Conserved RNA-Binding Proteins are Required for Dendrite Morphogenesis in Caenorhabditis elegans Sensory Neurons. G3: Genes, Genomics, Genetics 5(4): 639-653. DOI: 10.1534/g3.115.017327.
Vrailas-Mortimer, A., S.M. Ryan, M.J. Avey, N.T. Mortimer, H. Dowse, S. Sanyal. 2014. p38 MAP Kinase regulates circadian rhythms in Drosophila. Journal of Biological Rhythms 29(6): 411-426. DOI: 10.1177/0748730414555183.
Mortimer, N.T., J. Goecks, B.Z. Kacsoh, J.A. Mobley, G.J. Bowersock, J. Taylor, T.A. Schlenke. 2013. Parasitoid wasp venom SERCA regulates Drosophila calcium levels and inhibits cellular immunity. Proceedings of the National Academy of Sciences USA (PNAS) 110(23): 9427-9432. DOI: 10.1073/pnas.1222351110.
Goecks, J., N.T. Mortimer, J.A. Mobley, G.J. Bowersock, J. Taylor, T.A. Schlenke. 2013 Integrative approach reveals composition of endoparasitoid wasp venoms. PLOS One 8(5): e64125. DOI: 10.1371/journal.pone.0064125.
Kacsoh, B.Z., Z.R. Lynch, N.T. Mortimer, T.A. Schlenke. 2013. Fruit flies medicate offspring after seeing parasites. Science 339(6122): 947-950. DOI: 10.1126/science.1229625.
Mortimer, N.T., K.H. Moberg. 2013. The archipelago ubiquitin ligase subunit acts in target tissue to restrict tracheal terminal cell branching and hypoxic-induced gene expression. PLOS Genetics 9(2): e1003314. DOI: 10.1371/journal.pgen.1003314.
Mortimer, N.T., B.Z. Kacsoh, E.S. Keebaugh, T.A. Schlenke. 2012. Mgat1-dependent N-glycosylation of membrane components primes Drosophila melanogaster blood cells for the cellular encapsulation response. PLOS Pathogens 8(7): e1002819. DOI: 10.1371/journal.ppat.1002819.
Mortimer, N.T., K.H. Moberg. 2009. Regulation of Drosophila embryonic tracheogenesis by dVHL and hypoxia. Developmental Biology 329(2): 294-305. DOI: 10.1016/j.ydbio.2009.03.001.
Mortimer, N.T., K.H. Moberg. 2007. The Drosophila F-box protein Archipelago controls levels of the Trachealess transcription factor in the embryonic tracheal system. Developmental Biology 312(2): 560-571. DOI: 10.1016/j.ydbio.2007.10.002.
Suli, A., N.T. Mortimer, I. Shepherd, C.B. Chien. 2006. Netrin/DCC signaling controls contralateral dendrites of octavolateralis efferent neurons. Journal of Neuroscience 26(51): 13328-13337. DOI: 10.1523/JNEUROSCI.2858-06.2006.
Rogers, E.M., C.A. Brennan, N.T. Mortimer, S. Cook, A.R. Morris, K. Moses. 2005. Pointed regulates an eye-specific transcriptional enhancer in the Drosophila hedgehog gene, which is required for the movement of the morphogenetic furrow. Development 132(21): 4833-4843. DOI: 10.1242/dev.02061.
Yedvobnick, B., A. Kumar, P. Chaudhury, J. Opraseuth, N.T. Mortimer, K.M. Bhat. 2004. Differential effects of Drosophila mastermind on asymmetric cell fate specification and neuroblast formation. Genetics 166(3): 1281-1289. DOI: 10.1534/genetics.166.3.1281.
Preprints
Kr, P., N.T. Mortimer. Loss of self-tolerance leads to altered gene expression and IMD pathway activation in Drosophila melanogaster. bioRxiv DOI: 10.1101/2021.11.19.469298. In revision
Brantley, S.E., N.T. Mortimer and T.A. Schlenke. Host JAK/Stat activity is a target of endoparasitoid wasp virulence strategies. bioRxiv DOI: 10.1101/423335. Preparing submission
Invited Reviews
Elgin, S.C.R., The Genomics Education Partnership. 2017. The GEP: Crowd-Sourcing Big Data with Undergraduates. Trends in Genetics 33(2): 81-85. doi: 10.1016/j.tig.2016.11.004.
Mortimer, N.T. 2013. Parasitoid wasp virulence: a window into fly immunity. Fly 7(4): 242-248. doi: 10.4161/fly.26484.
Refereed Papers
Waring, A.L., J. Hill, B.M. Allen, N.M. Bretz, N. Le, P. Kr, D. Fuss, N.T. Mortimer. 2022. Meta-analysis of immune induced gene expression changes in diverse Drosophila melanogaster innate immune responses. Special Issue: Insect Bioinformatics. Insects, 13(5): 490. DOI: 10.3390/insects13050490.
Sultana, S., M.E. Crompton, K. Meurer, O. Jankiewicz, G.H. Morales, C. Johnson, E. Horbach, K.P. Hoffmann, P. Kr, R. Shah, G.M. Anderson, N.T. Mortimer, J.E. Schmitz, M. Hadjifrangiskou, A. Foti, J.U. Dahl. 2022. Redox-Mediated Inactivation of the Transcriptional Repressor RcrR is Responsible for Uropathogenic Escherichia coli's Increased Resistance to Reactive Chlorine Species. mBio, in press. DOI: 10.1128/mbio.01926-22.
Lopatto, D., et al. 2022. Student attitudes contribute to the effectiveness of a genomics CURE. J. Microbiol Biol Educ, DOI: 10.1128/jmbe.00208-21.
Thompson, C.F., K.E. Hodges, N.T. Mortimer, A.D. Vrailas-Mortimer, S.K. Sakaluk, M.E. Hauber. 2022. Avian eggshell coloration predicts shell-matrix protoporphyrin content. Canadian J of Zoology, 100: 77-81. DOI: 10.1139/cjz-2021-0134.
Mortimer, N.T., M.L. Fischer, A.L. Waring, P. Kr, B.Z. Kacsoh, S.E. Brantley, E.S. Keebaugh, J. Hill, C. Lark, J. Martin, P. Bains, J. Lee, A.D. Vrailas-Mortimer, T.A. Schlenke. 2021. Extracellular matrix protein N-glycosylation mediates immune self-tolerance in Drosophila melanogaster. PNAS, 118 (39): e2017460118. DOI: 10.1073/pnas.2017460118.
Ryan, S.M., M. Almassey, A.M. Burch, G. Ngo, J.M. Martin, D. Myers, D. Compton, S. Archie, L. Naeger, A. Salzman, A. Virola-Iarussi, M. Cross, S. Barbee, N.T. Mortimer, S. Sanyal, A.D. Vrailas-Mortimer. 2021. Drosophila p38 MAPK interacts with BAG-3/starvin to regulate age-dependent protein homeostasis. Aging Cell, 20 (11): e13481. DOI: 10.1111/acel.13481.
Calderon, S.J., S.Y. Chung, C.J. Fields, N.T. Mortimer. 2021. Children Tooth Brushing Behavior and Oral Microbiota: A Pilot Study. Oral, 1(2): 112-121. DOI: 10.3390/oral1020012.
Kr, P., J. Lee, N.T. Mortimer. 2021. The S1A protease family members CG10764 and CG4793 regulate cellular immunity in Drosophila. microPublication Biology: DOI: 10.17912/micropub.biology.000370.
Trainor, J.E., P. Kr, N.T. Mortimer. 2021. Immune Cell Production Is Targeted by Parasitoid Wasp Virulence in a Drosophila–Parasitoid Wasp Interaction. Pathogens, 10(1): 49. DOI: 10.3390/pathogens10010049.
Ryan, S.M., K. Wildman, B. Oceguera-Perez, S. Barbee, N.T. Mortimer, A. Vrailas-Mortimer. 2020. Evolutionarily Conserved Transcription Factors Drive the Oxidative Stress Response in Drosophila. J Exp Biology, 223: jeb221622. DOI: 10.1242/jeb.221622.
Sargent L., Y. Liu, W. Leung, N.T. Mortimer, D. Lopatto, J. Goecks, S.C.R. Elgin. 2020. G-OnRamp: Generating genome browsers to facilitate undergraduate-driven collaborative genome annotation. PLOS Computational Biology, 16(6): e1007863. DOI: 10.1371/journal.pcbi.1007863.
Hodges, K.E., N.T Mortimer, A.D. Vrailas-Mortimer, S.K. Sakaluk, C.F. Thompson. 2020. Connecting the dots: avian eggshell pigmentation, female condition and paternal provisioning effort. Biological Journal of the Linnean Society, 130(1): 114-127. DOI: 10.1093/biolinnean/blaa002.
Lopatto, D., et al. 2020. Facilitating Growth through Frustration: Using Genomics Research in a Course-Based Undergraduate Research Experience. J. Microbiol Biol Educ, 21(1): DOI: 10.1128/jmbe.v21i1.2005.
Alvarado, G., S.R. Holland, J. DePerez-Rasmussen, B.A. Jarvis, T. Telander, N. Wagner, A.L. Waring, A. Anast, B. Davis, A. Frank, K. Genenbacher, J. Larson, C. Mathis, A.E. Oates, N.A. Rhoades, L. Scott, J. Young, N.T. Mortimer. 2020. Bioinformatic analysis suggests potential mechanisms underlying parasitoid venom evolution and function. Genomics, 112: 1096-1104. DOI: 10.1016/j.ygeno.2019.06.022.
Leung, W., et al. 2017. Retrotransposons are the major contributors to the expansion of the Drosophila ananassae Muller F element. G3: Genes, Genomics, Genetics 7(8): 2439-2460. DOI: 10.1534/g3.117.040907.
Schachtner, L.T., I.E. Sola, D. Forand, S. Antonacci, A.J. Postovit, N.T. Mortimer, D.J. Killian, E.C. Olesnicky. 2015. Drosophila Shep and C. elegans SUP-26 are RNA-binding proteins that play diverse roles in nervous system development. Development Genes and Evolution 225(6): 319-330. DOI: 10.1007/s00427-015-0514-3.
Antonacci, S., D. Forand, M. Wolf, C. Tyus, J. Barney, L. Kellogg, M. Simon, G. Kerr, N.T. Mortimer, E.C. Olesnicky, D.J. Killian. 2015. Conserved RNA-Binding Proteins are Required for Dendrite Morphogenesis in Caenorhabditis elegans Sensory Neurons. G3: Genes, Genomics, Genetics 5(4): 639-653. DOI: 10.1534/g3.115.017327.
Vrailas-Mortimer, A., S.M. Ryan, M.J. Avey, N.T. Mortimer, H. Dowse, S. Sanyal. 2014. p38 MAP Kinase regulates circadian rhythms in Drosophila. Journal of Biological Rhythms 29(6): 411-426. DOI: 10.1177/0748730414555183.
Mortimer, N.T., J. Goecks, B.Z. Kacsoh, J.A. Mobley, G.J. Bowersock, J. Taylor, T.A. Schlenke. 2013. Parasitoid wasp venom SERCA regulates Drosophila calcium levels and inhibits cellular immunity. Proceedings of the National Academy of Sciences USA (PNAS) 110(23): 9427-9432. DOI: 10.1073/pnas.1222351110.
- Featured in: Science Signaling, The Journal of Experimental Biology, and Science Daily.
Goecks, J., N.T. Mortimer, J.A. Mobley, G.J. Bowersock, J. Taylor, T.A. Schlenke. 2013 Integrative approach reveals composition of endoparasitoid wasp venoms. PLOS One 8(5): e64125. DOI: 10.1371/journal.pone.0064125.
Kacsoh, B.Z., Z.R. Lynch, N.T. Mortimer, T.A. Schlenke. 2013. Fruit flies medicate offspring after seeing parasites. Science 339(6122): 947-950. DOI: 10.1126/science.1229625.
- Featured in: The Naked Scientists, National Geographic, and Live Science.
Mortimer, N.T., K.H. Moberg. 2013. The archipelago ubiquitin ligase subunit acts in target tissue to restrict tracheal terminal cell branching and hypoxic-induced gene expression. PLOS Genetics 9(2): e1003314. DOI: 10.1371/journal.pgen.1003314.
Mortimer, N.T., B.Z. Kacsoh, E.S. Keebaugh, T.A. Schlenke. 2012. Mgat1-dependent N-glycosylation of membrane components primes Drosophila melanogaster blood cells for the cellular encapsulation response. PLOS Pathogens 8(7): e1002819. DOI: 10.1371/journal.ppat.1002819.
Mortimer, N.T., K.H. Moberg. 2009. Regulation of Drosophila embryonic tracheogenesis by dVHL and hypoxia. Developmental Biology 329(2): 294-305. DOI: 10.1016/j.ydbio.2009.03.001.
Mortimer, N.T., K.H. Moberg. 2007. The Drosophila F-box protein Archipelago controls levels of the Trachealess transcription factor in the embryonic tracheal system. Developmental Biology 312(2): 560-571. DOI: 10.1016/j.ydbio.2007.10.002.
Suli, A., N.T. Mortimer, I. Shepherd, C.B. Chien. 2006. Netrin/DCC signaling controls contralateral dendrites of octavolateralis efferent neurons. Journal of Neuroscience 26(51): 13328-13337. DOI: 10.1523/JNEUROSCI.2858-06.2006.
Rogers, E.M., C.A. Brennan, N.T. Mortimer, S. Cook, A.R. Morris, K. Moses. 2005. Pointed regulates an eye-specific transcriptional enhancer in the Drosophila hedgehog gene, which is required for the movement of the morphogenetic furrow. Development 132(21): 4833-4843. DOI: 10.1242/dev.02061.
Yedvobnick, B., A. Kumar, P. Chaudhury, J. Opraseuth, N.T. Mortimer, K.M. Bhat. 2004. Differential effects of Drosophila mastermind on asymmetric cell fate specification and neuroblast formation. Genetics 166(3): 1281-1289. DOI: 10.1534/genetics.166.3.1281.
Preprints
Kr, P., N.T. Mortimer. Loss of self-tolerance leads to altered gene expression and IMD pathway activation in Drosophila melanogaster. bioRxiv DOI: 10.1101/2021.11.19.469298. In revision
Brantley, S.E., N.T. Mortimer and T.A. Schlenke. Host JAK/Stat activity is a target of endoparasitoid wasp virulence strategies. bioRxiv DOI: 10.1101/423335. Preparing submission
Invited Reviews
Elgin, S.C.R., The Genomics Education Partnership. 2017. The GEP: Crowd-Sourcing Big Data with Undergraduates. Trends in Genetics 33(2): 81-85. doi: 10.1016/j.tig.2016.11.004.
Mortimer, N.T. 2013. Parasitoid wasp virulence: a window into fly immunity. Fly 7(4): 242-248. doi: 10.4161/fly.26484.
